Abcam, ab121711, Anti-C7orf51 antibody

Size: 100µL
Rabbit Polyclonal C7orf51 antibody. Suitable for IHC-P, WB, ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human NYAP1 aa 500-650.
Key facts
Host species:Rabbit,
Clonality:Polyclonal,
Isotype:IgG,
Carrier free:No,
Reacts with:Human,
Applications:WB, IHC-P, ICC/IFSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:Recombinant Fragment Protein within Human NYAP1 aa 500-650. The exact immunogen used to generate this antibody is proprietary information.Q6ZVC0

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Immunogen, Storage buffer-pH: 7.2Preservative: 0.02% Sodium azideConstituents: PBS, 40% Glycerol (glycerin, glycerine), Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
C7orf51 also known as UPF0670 protein C7orf51 is a protein with a molecular weight of approximately 26 kDa. It is expressed in various tissues with higher expression observed in the liver and kidney. Mechanically C7orf51 is involved in intracellular signaling and cellular homeostasis. Its role may include acting as a scaffold or facilitator in larger protein complexes although its precise molecular functions are still under investigation.
Biological function summary
The protein contributes to cellular processes such as cell growth and maintenance. C7orf51 is often part of multi-protein complexes that modulate cellular responses to environmental changes. These complexes can influence metabolic processes and affect the stability of other intracellular proteins. Its interaction partners suggest a role in managing the balance between cell proliferation and apoptosis especially under stress conditions.
Pathways
C7orf51 interacts with several intracellular signaling cascades including the AKT signaling pathway and the mTOR pathway. These pathways are critical for regulating cell growth survival and metabolism. Within these pathways C7orf51 is thought to interact with proteins like AKT1 and MTOR modulating their activity to ensure appropriate cellular responses to external stimuli such as nutrient availability and hormonal signals.
Research implicates C7orf51 in metabolic disorders and cancer. Metabolic syndrome might involve dysregulation of pathways where C7orf51 plays a role affecting energy homeostasis and lipid metabolism. In cancer alterations in the pathways associated with C7orf51 like the mTOR pathway contribute to unchecked cell proliferation. Associations with proteins like AKT1 and MTOR in these diseases highlight the importance of C7orf51's regulatory function in these pathways.