Abcam, ab122117, Anti-TMEM61 antibody

Size: 100µL
Rabbit Polyclonal TMEM61 antibody. Suitable for IHC-P and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human TMEM61 aa 50 to C-terminus.
Key facts
Host species:Rabbit,
Clonality:Polyclonal,
Isotype:IgG,
Carrier free:No,
Reacts with:Human,
Applications:IHC-PSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:Recombinant Fragment Protein within Human TMEM61 aa 50 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.Q8N0U2

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Immunogen, Storage buffer-pH: 7.2Preservative: 0.02% Sodium azideConstituents: PBS, 40% Glycerol (glycerin, glycerine), Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
TMEM61 also known as Transmembrane Protein 61 is a protein encoded by the TMEM61 gene. It has an approximate mass of 21 kDa and spans the membrane suggesting its role as a membrane-associated protein. TMEM61 is expressed widely but exhibits higher expression levels in tissues such as brain and testis. The protein structure suggests potential involvement in signal transmission across cell membranes.
Biological function summary
TMEM61 plays a role in membrane-associated cellular processes. While not much is known about its specific biological functions researchers study it as part of a protein complex that might be integral to maintaining cellular membrane integrity. Evidence suggests TMEM61 could be involved in cellular transport mechanisms owing to its transmembrane nature.
Pathways
TMEM61 could play a part in pathways related to cellular transport and signal transduction. Researchers are investigating its role in the MAPK signaling pathway which involves proteins like ERK1/2. This pathway affects cell division differentiation and stress responses. TMEM61 may interact with other transmembrane proteins influencing these cellular processes.
Current research indicates potential involvement of TMEM61 in neurological disorders possibly linked to its expression in brain tissue. Researchers also examine its role in cancer due to its expression in testis and potential regulation of cell growth. TMEM61 may interact with proteins like PTEN which play roles in tumor suppression and are significant in cancer research.