Abcam, ab122317, Anti-GPR155 antibody

Size: 100µL
Rabbit Polyclonal GPR155 antibody. Suitable for IHC-P and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human GPR155 aa 700-800.
Key facts
Host species:Rabbit,
Clonality:Polyclonal,
Isotype:IgG,
Carrier free:No,
Reacts with:Human,
Applications:IHC-PSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:Recombinant Fragment Protein within Human GPR155 aa 700-800. The exact immunogen used to generate this antibody is proprietary information.Q7Z3F1

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Immunogen, Storage buffer-pH: 7.2Preservative: 0.02% Sodium azideConstituents: PBS, 40% Glycerol (glycerin, glycerine), Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
The GPR155 protein also known as G protein-coupled receptor 155 is an orphan receptor with a molecular mass of approximately 97 kDa. This protein belongs to the GPCR family which typically transmits signals from outside the cell to inside. GPR155 has been found expressed mainly in the brain indicating its potential role in neural function. Researchers have investigated its expression in various tissues but higher levels are often observed within neuronal cells.
Biological function summary
GPR155 influences signaling processes that are significant for neuronal development and function. Although not extensively characterized it is thought to be part of receptor complexes that regulate intracellular signaling cascades. Its specific role in these complexes remains to be fully understood yet it's suggested to act in coordination with other proteins involved in brain physiology.
Pathways
GPR155 participates in essential neural signaling pathways that are important for maintaining neuronal health. It is believed to interact with components of the Wnt signaling pathway known for regulating cellular processes involved in brain development. Additionally GPR155 shares pathway involvement with proteins such as PGR22 which suggests a broader regulatory role in signaling networks important for brain function.
GPR155 has connections to neurological conditions like autism spectrum disorders. Abnormal expression levels of GPR155 have been observed in patients with such conditions suggesting its potential role in disease mechanisms. It interacts with other proteins implicated in these disorders such as PGR22 highlighting a network of interactions that may contribute to pathophysiology. Further research is necessary to fully elucidate these connections and their clinical implications.