Abcam, ab125084, Anti-C14orf133 antibody

Size: 100µg
Rabbit Polyclonal C14orf133 antibody. Suitable for IP, WB and reacts with Human, Mouse samples. Cited in 4 publications. Immunogen corresponding to Synthetic Peptide within Human VIPAS39 aa 400 to C-terminus.
Key facts
Host species:Rabbit,
Clonality:Polyclonal,
Isotype:IgG,
Carrier free:No,
Reacts with:Human, Mouse,
Applications:IP, WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:Synthetic Peptide within Human VIPAS39 aa 400 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.Q9H9C1

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Immunogen, Purification notes-ab125084 was affinity purified using an epitope specific to C14orf133 immobilized on solid support., Storage buffer-pH: 7 - 8Preservative: 0.09% Sodium azideConstituents: 99% Tris citrate/phosphate, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
The C14orf133 protein also known as chromosome 14 open reading frame 133 is an intriguing target in biological research. This protein has a molecular mass of approximately 45 kDa. C14orf133 expression is detected across various tissues but especially noted in the brain and liver suggesting a role in specific physiological processes. It does not have an extensively documented function yet some studies indicate involvement in cellular structures and processes.
Biological function summary
The protein C14orf133 participates in maintaining cellular functions through association with certain complexes. It might be involved in cellular organization or structural maintenance. Although detailed mechanisms are still emerging its expression pattern suggests an influence in central processes related to cellular architecture or signal transduction within these tissues possibly interconnected with broader cellular systems.
Pathways
The protein C14orf133 often influences or interacts with well-defined cellular pathways. It might engage in cellular signaling pathways or have a role linked to actin cytoskeleton organization. Related proteins in these pathways might include actin-binding proteins or signaling mediators that guide cellular responses. Understanding its exact role in these pathways can highlight its impact on cellular behavior and physiological function.
Research suggests C14orf133 may relate to conditions affecting the nervous system or liver. Connections to neurodegenerative diseases or hepatic dysfunctions have been proposed. Proteins interacting with C14orf133 in these contexts may include those involved in neurogenic signaling or metabolic regulation within the liver. Investigating these connections further may uncover potential therapeutic insights or diagnostic markers related to these diseases.