Abcam, ab126543, Anti-C1orf192 antibody

Size: 100µL
Rabbit Polyclonal C1orf192 antibody. Suitable for IHC-P, ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human CFAP126 aa 100 to C-terminus.
Key facts
Host species:Rabbit,
Clonality:Polyclonal,
Isotype:IgG,
Carrier free:No,
Reacts with:Human,
Applications:ICC/IF, IHC-PSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:Recombinant Fragment Protein within Human CFAP126 aa 100 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.Q5VTH2

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Immunogen, Storage buffer-pH: 7.2Preservative: 0.02% Sodium azideConstituents: PBS, 40% Glycerol (glycerin, glycerine), Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
C1orf192 also referred to as Chromosome 1 open reading frame 192 has a molecular mass of approximately 34 kDa. It is expressed in multiple tissues throughout the body but shows higher levels in specific regions like the liver and the brain. Mechanically C1orf192 is hypothesized to function as a binding protein possibly interacting with other proteins to facilitate cellular processes. Its specific domains suggest a role in protein-protein interactions although detailed binding partners and the exact nature of its interactions remain under investigation.
Biological function summary
C1orf192 integrates into cellular functions that are essential for maintaining normal cellular homeostasis. It appears to be involved in regulatory activities though the details of its biological role are still studied. C1orf192 does not seem to be a part of large well-characterized complexes which makes it a harder target for straightforward functional dissection. However ongoing research suggests its potential involvement in modulating cellular signal transduction and possibly influencing cell cycle progression.
Pathways
Our understanding of C1orf192 involves its potential participation in signal transduction and cellular response pathways. It may interact with proteins involved in the AKT signaling pathway which is essential for regulating cell survival and proliferation. While direct interactors in the pathway are not comprehensively established C1orf192 might connect to proteins like PI3K or mTOR suggesting a putative role in these pathways. The exact integration of C1orf192 within these networks requires further experimental validation.
C1orf192 has been linked to neurological conditions suggesting its role in brain-specific functional pathways. Observations connect this target to Alzheimer's Disease where its altered expression might impact disease progression. Furthermore its potential interaction with Beta-amyloid precursor proteins and tau proteins highlights the need to explore its contribution to neurodegenerative mechanisms. Continued studies are important to establish precise causative relationships and therapeutic potentials.