Abcam, ab126880, Anti-ZNF652 antibody

Size: 200µL
Goat Polyclonal ZNF652 antibody. Suitable for WB and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Synthetic Peptide within Human ZNF652 aa 550 to C-terminus.
Key facts
Host species:Goat,
Clonality:Polyclonal,
Isotype:IgG,
Carrier free:No,
Reacts with:Human,
Applications:WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:Synthetic Peptide within Human ZNF652 aa 550 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.Q9Y2D9

Product details:
Reported variants represent identical protein: NP_055712.1, NP_001138837.1.

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Immunogen, Purification notes-ab126880 is purified from Goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide., Storage buffer-pH: 7.3Preservative: 0.02% Sodium azideConstituents: 99% Tris buffered saline, 0.5% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
ZNF652 also known as zinc finger protein 652 is a transcription factor involved in regulating gene expression. It has a molecular mass of approximately 68 kDa. ZNF652 is expressed in various tissues with higher levels in the brain liver and lung. The protein contains zinc finger motifs which allow it to bind specific DNA sequences leading to modulation of transcription.
Biological function summary
Zinc finger proteins like ZNF652 contribute to cell proliferation and differentiation. It likely functions as part of a multiprotein complex but specific interaction partners are still under investigation. The protein plays a role in the regulation of other transcription factors and in determining cellular response to external signals.
Pathways
ZNF652 integrates into the regulation of transcriptional networks. It is active in pathways related to cellular growth and differentiation. ZNF652 works closely with other transcription factors like the MYC oncogene influencing cell cycle and proliferation through regulatory feedback loops.
Researchers associate ZNF652 with various cancers such as breast and prostate cancer. Changes in ZNF652 expression levels or mutations can contribute to tumorigenesis. ZNF652 interacts with proteins like TP53 an important tumor suppressor highlighting its relevance in cancer pathways.