Abcam, ab141025, Bexarotene, RXR agonist

Size: 10mg / 50mg
MW 348.48 g/mol, Purity >99%. Potent RXR agonist (K i values are 30.5, 16.4, 19.7, >1000 for RXRα, RXRβ, RXRγ and RAR respectively). Inhibits neurodegeneration and displays anticancer activity in vivo and in vitro . Blood-brain barrier permeable.
Key facts
CAS number:153559-49-0,
Purity:>99%,
Form:SolidSee storage information,
Molecular weight:348.48 g/mol,
Molecular formula:C24H28O2,
Nature:Synthetic,
Solubility:Soluble in ethanol to 25 mMSoluble in DMSO to 50 mM,
Biological description:Potent RXR agonist (Ki values are 30.5, 16.4, 19.7, >1000 for RXRα, RXRβ, RXRγ and RAR respectively). Inhibits neurodegeneration and displays anticancer activity in vivo and in vitro. Blood-brain barrier permeable.,
Canonical smiles:O=C(O)C1CCC(CC1)C(=C)C2CC3C(CC2C)C(C)(C)CCC3(C)C,
InChi:InChI=1S/C24H28O2/c1-15-13-20-21(24(5,6)12-11-23(20,3)4)14-19(15)16(2)17-7-9-18(10-8-17)22(25)26/h7-10,13-14H,2,11-12H2,1,3-6H3,(H,25,26),
InChiKey:NAVMQTYZDKMPEU-UHFFFAOYSA-N,
IUPAC Name:4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoic acid

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-It is important to note that this product is reported to be light sensitive, Store in the dark, Store under desiccating conditions