Abcam, ab141107, CPT 11 (Irinotecan), DNA topoisomerase I inhibitor

Size: 10mg / 50mg
MW 623.1 Da, Purity >99%. Potent DNA topoisomerase I inhibitor. Displays antitumor activity against a variety of tumor types. Active metabolite SN38 (ab141108) also available.
Key facts
CAS number:100286-90-6,
Purity:>99%,
Form:SolidSee storage information,
Molecular weight:623.1 Da,
Molecular formula:C33H39ClN4O6,
PubChem:74990,
Nature:Synthetic,
Solubility:Soluble in water to 5 mMSoluble in DMSO to 100 mM,
Biochemical name:Irinotecan hydrochloride,
Biological description:Potent DNA topoisomerase I inhibitor. Displays antitumor activity against a variety of tumor types. Active metabolite SN38 (ab141108) also available.,
Canonical smiles:CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)C4(CC)O)C2=NC5=C1C=C(C=C5)OC(=O)N6CCC(CC6)N7CCCCC7.Cl,
Isomeric smiles:CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)[C@@]4(CC)O)C2=NC5=C1C=C(C=C5)OC(=O)N6CCC(CC6)N7CCCCC7.Cl,
InChi:InChI=1S/C33H38N4O6.ClH/c1-3-22-23-16-21(43-32(40)36-14-10-20(11-15-36)35-12-6-5-7-13-35)8-9-27(23)34-29-24(22)18-37-28(29)17-26-25(30(37)38)19-42-31(39)33(26,41)4-2;/h8-9,16-17,20,41H,3-7,10-15,18-19H2,1-2H3;1H/t33-;/m0./s1,
InChiKey:GURKHSYORGJETM-WAQYZQTGSA-N,
IUPAC Name:[(19S)-10,19-diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaen-7-yl] 4-piperidin-1-ylpiperidine-1-carboxylate;hydrochloride

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-The product can be stored for up to 12 months