Abcam, ab141190, Sinomenine hydrochloride, Morphinan analog

Size: 50mg
MW 365.8 Da, Purity >98%. Natural anti-inflammatory morphinan analog, able to weakly bind to the μ-opioid receptor. Potently releases histamine following mast cell degranulation. Inhibits oligomeric amyloid-β-induced increases in ROS, NO and other inflammatory molecules. Stimulates acute renewal of human embryonic stem cells (ESCs) in vitro .
Key facts
CAS number:6080-33-7,
Purity:>98%,
Form:SolidSee storage information,
Source:Sinomenium acutum,
Molecular weight:365.8 Da,
Molecular formula:C19H24ClNO4,
PubChem:5464452,
Nature:Native,
Solubility:Soluble in water to 100 mM,
Biochemical name:Sinomenine hydrochloride,
Biological description:Natural anti-inflammatory morphinan analog, able to weakly bind to the μ-opioid receptor. Potently releases histamine following mast cell degranulation. Inhibits oligomeric amyloid-β-induced increases in ROS, NO and other inflammatory molecules. Stimulates acute renewal of human embryonic stem cells (ESCs) in vitro.,
Canonical smiles:CN1CCC23CC(=O)C(=CC2C1CC4=C3C(=C(C=C4)OC)O)OC.Cl,
Isomeric smiles:CN1CC[C@@]23CC(=O)C(=C[C@@H]2[C@@H]1CC4=C3C(=C(C=C4)OC)O)OC.Cl,
InChi:InChI=1S/C19H23NO4.ClH/c1-20-7-6-19-10-14(21)16(24-3)9-12(19)13(20)8-11-4-5-15(23-2)18(22)17(11)19;/h4-5,9,12-13,22H,6-8,10H2,1-3H3;1H/t12-,13+,19-;/m1./s1,
InChiKey:YMEVIMJAUHZFMW-VUIDNZEBSA-N,
IUPAC Name:(1R,9S,10S)-3-hydroxy-4,12-dimethoxy-17-methyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5,11-tetraen-13-one;hydrochloride

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months