Abcam, ab141238, Olomoucine II, CDK/cyclin inhibitor

Size: 1mg / 5mg
MW 370.4 Da, Purity >98%. CDK/cyclin inhibitor (IC 50 values are 7.6 (CDK1/cyclin B), 0.1 (CDK2/cyclin E), 19.8 (CDK4/cyclin D1), 0.45 (CDK7/cyclin H) and 0.06 (CDK9/cyclin T) μM). Shows an IC 50 of >100 μM for 10 other kinases. Antiproliferative and anticancer activity in vitro .
Key facts
CAS number:500735-47-7,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:370.4 Da,
Molecular formula:C19H26N6O2,
PubChem:5494414,
Nature:Synthetic,
Solubility:Soluble in DMSO to 100 mMSoluble in ethanol to 50 mM,
Biochemical name:Olomoucine II,
Biological description:CDK/cyclin inhibitor (IC50 values are 7.6 (CDK1/cyclin B), 0.1 (CDK2/cyclin E), 19.8 (CDK4/cyclin D1), 0.45 (CDK7/cyclin H) and 0.06 (CDK9/cyclin T) μM). Shows an IC50 of >100 μM for 10 other kinases. Antiproliferative and anticancer activity in vitro.,
Canonical smiles:CCC(CO)NC1=NC(=C2C(=N1)N(C=N2)C(C)C)NCC3=CC=CC=C3O,
Isomeric smiles:CC[C@H](CO)NC1=NC(=C2C(=N1)N(C=N2)C(C)C)NCC3=CC=CC=C3O,
InChi:InChI=1S/C19H26N6O2/c1-4-14(10-26)22-19-23-17(20-9-13-7-5-6-8-15(13)27)16-18(24-19)25(11-21-16)12(2)3/h5-8,11-12,14,26-27H,4,9-10H2,1-3H3,(H2,20,22,23,24)/t14-/m1/s1,
InChiKey:NDUVSANREQEDRE-CQSZACIVSA-N,
IUPAC Name:2-[[[2-[[(2R)-1-hydroxybutan-2-yl]amino]-9-propan-2-ylpurin-6-yl]amino]methyl]phenol

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months