Abcam, ab141262, HNHA, HDAC inhibitor

Size: 5mg / 25mg
MW 303.4 Da, Purity >98%. Potent, cell-permeable HDAC inhibitor (IC 50 = 100 nM). Induces histone hyperacetylation and p21 transcription with concomitant inhibition of cell cycle progression. Arrests cell cycle at G 1 /S phase in cancer cells. Antitumor and antiangiogenic agent. Active in vivo and in vitro .
Key facts
CAS number:926908-04-5,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:303.4 Da,
Molecular formula:C17H21NO2S,
PubChem:16126782,
Nature:Synthetic,
Solubility:Soluble in DMSO to 100 mM,
Biochemical name:N-hydroxy-7-(naphthalen-2-ylthio)heptanamide,
Biological description:Potent, cell-permeable HDAC inhibitor (IC50 = 100 nM). Induces histone hyperacetylation and p21 transcription with concomitant inhibition of cell cycle progression. Arrests cell cycle at G1/S phase in cancer cells. Antitumor and antiangiogenic agent. Active in vivo and in vitro.,
Canonical smiles:C1=CC=C2C=C(C=CC2=C1)SCCCCCCC(=O)NO,
InChi:InChI=1S/C17H21NO2S/c19-17(18-20)9-3-1-2-6-12-21-16-11-10-14-7-4-5-8-15(14)13-16/h4-5,7-8,10-11,13,20H,1-3,6,9,12H2,(H,18,19),
InChiKey:KPNNXHVGOKRBEF-UHFFFAOYSA-N,
IUPAC Name:N-hydroxy-7-naphthalen-2-ylsulfanylheptanamide

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C