Abcam, ab141484, Z-FA-FMK, Cysteine protease inhibitor

Size: 1mg / 5mg
MW 386.4 Da, Purity >95%. Irreversible cysteine protease inhibitor. Cell-permeable caspase effector inhibitor. Selectively inhibits recombinant effector caspases 2, -3, -6, and -7. Inhibits cathepsin B, L, and S, papain and cruzain. Induces apoptosis and necrosis. Shows anti-inflammatory effects in vivo. Negative control for caspase inhibitors. Liquid form also available (ab141384).
Key facts
CAS number:96922-64-4,
Purity:>95%,
Form:SolidSee storage information,
Molecular weight:386.4 Da,
Molecular formula:C21H23FN2O4,
PubChem:122019,
Nature:Synthetic,
Solubility:Soluble in DMSO to 10 mM,
Biochemical name:Benzyloxycarbonylphenylalanyl-alanine fluoromethyl ketone,
Biological description:Irreversible cysteine protease inhibitor. Cell-permeable caspase effector inhibitor. Selectively inhibits recombinant effector caspases 2, -3, -6, and -7. Inhibits cathepsin B, L, and S, papain and cruzain. Induces apoptosis and necrosis. Shows anti-inflammatory effects in vivo. Negative control for caspase inhibitors. Liquid form also available (ab141384),
Canonical smiles:CC(C(=O)CF)NC(=O)C(CC1=CC=CC=C1)NC(=O)OCC2=CC=CC=C2,
InChi:InChI=1S/C21H23FN2O4/c1-15(19(25)13-22)23-20(26)18(12-16-8-4-2-5-9-16)24-21(27)28-14-17-10-6-3-7-11-17/h2-11,15,18H,12-14H2,1H3,(H,23,26)(H,24,27),
InChiKey:ASXVEBPEZMSPHB-UHFFFAOYSA-N,
IUPAC Name:benzyl N-[1-[(4-fluoro-3-oxobutan-2-yl)amino]-1-oxo-3-phenylpropan-2-yl]carbamate

Product details:
This product is manufactured by BioVision, an Abcam company and was previously called 1986 Z-FA-FMK. 1986-5 is the same size as the 5 mg size of ab141484.

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months