Abcam, ab141503, Garcinol, HAT p300 and PCAF inhibitor

Size: 5mg / 25mg
MW 602.8 Da, Purity >95%. Potent histone acetyltransferase p300 and PCAF inhibitor (IC 50 values are 7 and 5 μM for p300 and PCAF respectively). Pleiotropic agent. Strongly inhibits chromatin transcription and induces apoptosis. Inhibits histone acetylation in vivo . Antioxidant and chemoprotective agent.
Key facts
CAS number:78824-30-3,
Purity:>95%,
Molecular weight:602.8 Da,
Molecular formula:C38H50O6,
PubChem:3531,
Nature:Synthetic,
Solubility:Soluble in DMSO to 25 mMSoluble in ethanol to 25 mM,
Biochemical name:Camboginol,
Biological description:Potent histone acetyltransferase p300 and PCAF inhibitor (IC50 values are 7 and 5 μM for p300 and PCAF respectively). Pleiotropic agent. Strongly inhibits chromatin transcription and induces apoptosis. Inhibits histone acetylation in vivo. Antioxidant and chemoprotective agent.,
Canonical smiles:CC(=CCC1CC2(C(=O)C(=C(C3=CC(=C(C=C3)O)O)O)C(=O)C(C2=O)(C1(C)C)CC=C(C)C)CC(CC=C(C)C)C(=C)C)C,
InChi:InChI=1S/C38H50O6/c1-22(2)11-13-27(25(7)8)20-37-21-28(15-12-23(3)4)36(9,10)38(35(37)44,18-17-24(5)6)34(43)31(33(37)42)32(41)26-14-16-29(39)30(40)19-26/h11-12,14,16-17,19,27-28,39-41H,7,13,15,18,20-21H2,1-6,8-10H3,
InChiKey:DTTONLKLWRTCAB-UHFFFAOYSA-N,
IUPAC Name:3-[(3,4-dihydroxyphenyl)-hydroxymethylidene]-6,6-dimethyl-5,7-bis(3-methylbut-2-enyl)-1-(5-methyl-2-prop-1-en-2-ylhex-4-enyl)bicyclo[3.3.1]nonane-2,4,9-trione

Product details:
This product is manufactured by BioVision, an Abcam company and was previously called 2088 Garcinol. 2088-25 is the same size as the 25 mg size of ab141503.

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months