Abcam, ab142126, WHI-P131 hydrochloride, JAK3 inhibitor

Size: 10mg / 25mg
MW 297.31 Da, Purity >98%. Cell-permeable Janus kinase 3 (JAK3) inhibitor (IC 50 values of 9.1 μM and 78 μM for human and mouse recombinant proteins respectively). Selective versus JAK1, JAK2, SYK, BTK and LYN tyrosine kinases.
Key facts
CAS number:202475-60-3,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:297.31 Da,
Molecular formula:C16H15N3O3,
PubChem:3794,
Nature:Synthetic,
Solubility:Soluble in DMSO to 100 mM,
Biochemical name:Janex-1,
Biological description:Cell-permeable Janus kinase 3 (JAK3) inhibitor (IC50 values of 9.1 μM and 78 μM for human and mouse recombinant proteins respectively). Selective versus JAK1, JAK2, SYK, BTK and LYN tyrosine kinases.,
Canonical smiles:COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=C(C=C3)O)OC,
InChi:InChI=1S/C16H15N3O3/c1-21-14-7-12-13(8-15(14)22-2)17-9-18-16(12)19-10-3-5-11(20)6-4-10/h3-9,20H,1-2H3,(H,17,18,19),
InChiKey:HOZUXBLMYUPGPZ-UHFFFAOYSA-N,
IUPAC Name:4-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C