Abcam, ab142161, NSC 23766 trihydrochloride, Rac-1 inhibitor

Size: 1mg / 5mg
MW 531 Da, Purity >98%. Selective Rac-1 inhibitor. Blocks Rac-specific guanine nucleotide exchange factors TrioN and Tiam1 (IC 50 = 50 μM) without affecting Cdc42 or RhoA activation. Apoptotic and causes G1 cell cycle arrest in vitro . Cell-permeable. Active in vivo and centrally active.
Key facts
CAS number:733767-34-5,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:531 Da,
Molecular formula:C24H38Cl3N7,
PubChem:16759159,
Nature:Synthetic,
Solubility:Soluble in water to 100 mMSoluble in DMSO to 100 mM,
Biochemical name:NSC 23766 trihydrochloride,
Biological description:Selective Rac-1 inhibitor. Blocks Rac-specific guanine nucleotide exchange factors TrioN and Tiam1 (IC50 = 50 μM) without affecting Cdc42 or RhoA activation. Apoptotic and causes G1 cell cycle arrest in vitro. Cell-permeable. Active in vivo and centrally active.,
Canonical smiles:CCN(CC)CCCC(C)NC1=NC(=CC(=N1)NC2=CC3=C(C=C(N=C3C=C2)C)N)C.Cl.Cl.Cl,
InChi:InChI=1S/C24H35N7.3ClH/c1-6-31(7-2)12-8-9-16(3)27-24-28-18(5)14-23(30-24)29-19-10-11-22-20(15-19)21(25)13-17(4)26-22;;;/h10-11,13-16H,6-9,12H2,1-5H3,(H2,25,26)(H2,27,28,29,30);3*1H,
InChiKey:CPUHORIUXPQCHW-UHFFFAOYSA-N,
IUPAC Name:6-N-[2-[5-(diethylamino)pentan-2-ylamino]-6-methylpyrimidin-4-yl]-2-methylquinoline-4,6-diamine;trihydrochloride

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-Ambient, Appropriate long-term storage conditions-Ambient, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months