Abcam, ab142387, 5-Fluorouracil, RNA and DNA synthesis inhibitor

Size: 1g / 5g
MW 135.07 Da, Purity >98%. RNA and DNA synthesis inhibitor. Anticancer agent. Pyrimidine analog causing misincorporation of fluoronucleotides into DNA/RNA during synthesis. Thymidylate synthase inhibitor. Induces cell cycle arrest G1/S and apoptosis. Orally active.
Key facts
CAS number:1189492-99-6,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:135.07 Da,
Molecular formula:C4H5FN2O2,
PubChem:45039276,
Nature:Synthetic,
Solubility:Soluble in DMSO to 100 mM,
Biochemical name:5-Fluorodihydropyrimidine-2,4-dione-13C,15N2,
Biological description:RNA and DNA synthesis inhibitor. Anticancer agent. Pyrimidine analog causing misincorporation of fluoronucleotides into DNA/RNA during synthesis. Thymidylate synthase inhibitor. Induces cell cycle arrest G1/S and apoptosis. Orally active.,
Canonical smiles:C1C(C(=O)NC(=O)N1)F,
Isomeric smiles:C1C(C(=O)[15NH][13C](=O)[15NH]1)F,
InChi:InChI=1S/C4H5FN2O2/c5-2-1-6-4(9)7-3(2)8/h2H,1H2,(H2,6,7,8,9)/i4+1,6+1,7+1,
InChiKey:RAIRJKWTBBDDAR-XZQGXACKSA-N,
IUPAC Name:5-fluoro-(213C,1,3-15N2)1,3-diazinane-2,4-dione

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-Ambient, Appropriate long-term storage conditions-Ambient, Storage information-The product can be stored for up to 12 months