Abcam, ab144194, Atpenin A5, ubiquinone-binding site mitochondrial complex II inhibitor

Size: 250µg / 1mg
MW 366.2 Da, Purity >95%. Highly selective, potent ubiquinone-binding site mitochondrial complex II inhibitor (IC 50 values are 12 and 3.7 nM for nematode and mammalian mitochondria respectively). Stimulates mitochondrial K ATP channels. Shows anti-ischemic and cardioprotective effects in vivo. .
Key facts
CAS number:119509-24-9,
Purity:>95%,
Form:SolidSee storage information,
Molecular weight:366.2 Da,
Molecular formula:C15H21Cl2NO5,
PubChem:54676868,
Nature:Synthetic,
Solubility:Soluble in ethanolSoluble in DMSO,
Biochemical name:Atpenin A5,
Biological description:Highly selective, potent ubiquinone-binding site mitochondrial complex II inhibitor (IC50 values are 12 and 3.7 nM for nematode and mammalian mitochondria respectively). Stimulates mitochondrial KATP channels. Shows anti-ischemic and cardioprotective effects in vivo.,
Canonical smiles:CC(CC(C)C(=O)C1=C(C(=C(NC1=O)OC)OC)O)C(CCl)Cl,
Isomeric smiles:C[C@@H](C[C@H](C)C(=O)C1=C(C(=C(NC1=O)OC)OC)O)[C@H](CCl)Cl,
InChi:InChI=1S/C15H21Cl2NO5/c1-7(9(17)6-16)5-8(2)11(19)10-12(20)13(22-3)15(23-4)18-14(10)21/h7-9H,5-6H2,1-4H3,(H2,18,20,21)/t7-,8-,9-/m0/s1,
InChiKey:OVULNOOPECCZRG-CIUDSAMLSA-N,
IUPAC Name:3-[(2S,4S,5R)-5,6-dichloro-2,4-dimethylhexanoyl]-4-hydroxy-5,6-dimethoxy-1H-pyridin-2-one

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months