Abcam, ab144596, SMER3, SCFMet30 ubiquitin E3 ligase inhibitor

Size: 10mg / 50mg
MW 224.17 Da, Purity >98%. Cell permeable, selective SCFMet30 ubiquitin E3 ligase inhibitor. Enhances the action of rapamycin. Induces cell cycles arrest (IC50 = 10-30 μM). Active *in vivo.*.
Key facts
CAS number:67200-34-4,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:224.17 Da,
Molecular formula:C11H4N4O2,
PubChem:568763,
Nature:Synthetic,
Solubility:Soluble in DMSO to 100 mM,
Biochemical name:9H-Indeno[1,2-b][1,2,5]oxadiazolo[3,4-E]pyrazin-9-one,
Biological description:Cell permeable, selective SCFMet30 ubiquitin E3 ligase inhibitor. Enhances the action of rapamycin. Induces cell cycles arrest (IC50 = 10-30 μM). Active *in vivo.*,
Canonical smiles:C1=CC=C2C(=C1)C3=NC4=NON=C4N=C3C2=O,
InChi:InChI=1S/C11H4N4O2/c16-9-6-4-2-1-3-5(6)7-8(9)13-11-10(12-7)14-17-15-11/h1-4H,
InChiKey:SFSSAKVWCKFRHE-UHFFFAOYSA-N,
IUPAC Name:13-oxa-10,12,14,16-tetrazatetracyclo[7.7.0.02,7.011,15]hexadeca-1(16),2,4,6,9,11,14-heptaen-8-one

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-Ambient, Appropriate long-term storage conditions-Ambient, Storage information-The product can be stored for up to 12 months