Abcam, ab144820, WZ 4003, NUAK kinase inhibitor

Size: 5mg / 50mg
MW 497 Da, Purity >98%. Potent, selective NUAK kinase inhibitor (IC 50 values are 20 and 100 nM for NUAK1 and NUAK2, respectively). Impairs invasive potential of U2OS cells. Shows antiproliferative effects.
Key facts
CAS number:1214265-58-3,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:497 Da,
Molecular formula:C25H29ClN6O3,
PubChem:72200024,
Nature:Synthetic,
Solubility:Soluble in DMSO to 25 mM,
Biochemical name:N-(3-((5-chloro-2-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)oxy)phenyl)propionamide,
Biological description:Potent, selective NUAK kinase inhibitor (IC50 values are 20 and 100 nM for NUAK1 and NUAK2, respectively). Impairs invasive potential of U2OS cells. Shows antiproliferative effects.,
Canonical smiles:CCC(=O)NC1=CC(=CC=C1)OC2=NC(=NC=C2Cl)NC3=C(C=C(C=C3)N4CCN(CC4)C)OC,
InChi:InChI=1S/C25H29ClN6O3/c1-4-23(33)28-17-6-5-7-19(14-17)35-24-20(26)16-27-25(30-24)29-21-9-8-18(15-22(21)34-3)32-12-10-31(2)11-13-32/h5-9,14-16H,4,10-13H2,1-3H3,(H,28,33)(H,27,29,30),
InChiKey:SDGJBAUIGHSMRI-UHFFFAOYSA-N,
IUPAC Name:N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]propanamide

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months