Abcam, ab145231, IM 54 (2-(1H-Indol-3-yl)-3-pentylamino-maleimide), Necrosis inhibitor

Size: 1mg
MW 325.4 Da, Purity >98%. Potent, selective necrosis inhibitor (IC 50 = 3 μM, H 2 O 2 exposed HeLa cells). Reduces oxidative stress-induced necrosis without effecting anticancer drug-induced apoptosis. Inhibits oxidative stress-induced necrotic cell death in vivo. .
Key facts
CAS number:861891-50-1,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:325.4 Da,
Molecular formula:C19H23N3O2,
PubChem:16760577,
Nature:Synthetic,
Solubility:Soluble in ethanol to 25 mMSoluble in DMSO to 100 mM,
Biochemical name:1-Methyl-3-(1-methyl-1H-indol-3-yl)-4-(pentylamino)-1H-pyrrole-2,5-dione,
Biological description:Potent, selective necrosis inhibitor (IC50 = 3 μM, H2O2 exposed HeLa cells). Reduces oxidative stress-induced necrosis without effecting anticancer drug-induced apoptosis. Inhibits oxidative stress-induced necrotic cell death in vivo.,
Canonical smiles:CCCCCNC1=C(C(=O)N(C1=O)C)C2=CN(C3=CC=CC=C32)C,
InChi:InChI=1S/C19H23N3O2/c1-4-5-8-11-20-17-16(18(23)22(3)19(17)24)14-12-21(2)15-10-7-6-9-13(14)15/h6-7,9-10,12,20H,4-5,8,11H2,1-3H3,
InChiKey:SGLOMINNEBLJFF-UHFFFAOYSA-N,
IUPAC Name:1-methyl-3-(1-methylindol-3-yl)-4-(pentylamino)pyrrole-2,5-dione

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months