Abcam, ab145589, 3-Nitropropionic acid, Succinic dehydrogenase (complex II) inhibitor

Size: 50mg / 250mg
MW 119.08 Da, Purity >97%. Selective, irreversible succinic dehydrogenase (complex II) inhibitor. Induces mitochondrial citric acid cycle dysfunction, oxidative stress and cell death. Activates the Keap1-Nrf2-ARE pathway. Inhibits the MAPK and NF-κB pathways. Shows neurotoxic effects in vivo. .
Key facts
CAS number:504-88-1,
Purity:>97%,
Form:SolidSee storage information,
Molecular weight:119.08 Da,
Molecular formula:C3H5NO4,
PubChem:1678,
Nature:Synthetic,
Solubility:Soluble in ethanol to 100 mM,
Biochemical name:3-Nitropropionic acid,
Biological description:Selective, irreversible succinic dehydrogenase (complex II) inhibitor. Induces mitochondrial citric acid cycle dysfunction, oxidative stress and cell death. Activates the Keap1-Nrf2-ARE pathway. Inhibits the MAPK and NF-κB pathways. Shows neurotoxic effects in vivo.,
Canonical smiles:C(C[N+](=O)[O-])C(=O)O,
InChi:InChI=1S/C3H5NO4/c5-3(6)1-2-4(7)8/h1-2H2,(H,5,6),
InChiKey:WBLZUCOIBUDNBV-UHFFFAOYSA-N,
IUPAC Name:3-nitropropanoic acid

Product details:
This product is manufactured by BioVision, an Abcam company and was previously called 2093 3-Nitropropionic acid. 2093-250 is the same size as the 250 mg size of ab145589.

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months