Abcam, ab145636, Bufalin, Na+/K+-ATPase inhibitor

Size: 10mg / 50mg
MW 386.5 Da, Purity >98%. Na+/K+-ATPase inhibitor. Potent steroid receptor coactivators SRC-3 and SRC-1 inhibitor. Induces cell differentiation and apoptosis. Activates AP-1 via JNK. Shows antitumor effects *in vivo.*.
Key facts
CAS number:465-21-4,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:386.5 Da,
Molecular formula:C24H34O4,
PubChem:9547215,
Nature:Synthetic,
Solubility:Soluble in ethanol to 50 mM (with warming)Soluble in DMSO to 50 mM,
Biochemical name:Bufalin,
Biological description:Na+/K+-ATPase inhibitor. Potent steroid receptor coactivators SRC-3 and SRC-1 inhibitor. Induces cell differentiation and apoptosis. Activates AP-1 via JNK. Shows antitumor effects *in vivo.*,
Canonical smiles:CC12CCC(CC1CCC3C2CCC4(C3(CCC4C5=COC(=O)C=C5)O)C)O,
Isomeric smiles:C[C@]12CC[C@@H](C[C@H]1CC[C@@H]3[C@@H]2CC[C@]4([C@@]3(CC[C@@H]4C5=COC(=O)C=C5)O)C)O,
InChi:InChI=1S/C24H34O4/c1-22-10-7-17(25)13-16(22)4-5-20-19(22)8-11-23(2)18(9-12-24(20,23)27)15-3-6-21(26)28-14-15/h3,6,14,16-20,25,27H,4-5,7-13H2,1-2H3/t16-,17+,18-,19+,20-,22+,23-,24+/m1/s1,
InChiKey:QEEBRPGZBVVINN-BMPKRDENSA-N,
IUPAC Name:5-[(3S,5R,8R,9S,10S,13R,14S,17R)-3,14-dihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]pyran-2-one

Product details:
This product is manufactured by BioVision, an Abcam company and was previously called 2509 Bufalin. 2509-50 is the same size as the 50 mg size of ab145636.

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months