Abcam, ab146601, PD 184352 (CI-1040) (DMSO solution), MEK1/2 inhibitor

Size: 1mg
MW 478.7 Da, Purity >99%. Potent, highly selective ATP non-competitive MEK1/2 inhibitor. Enhances cisplatin (ab141398) dependent apoptosis. Shows antitumor effects in vivo. Orally active.
Key facts
CAS number:212631-79-3,
Purity:>99%,
Form:LiquidSee storage information,
Molecular weight:478.7 Da,
Molecular formula:C17H14ClF2IN2O2,
PubChem:6918454,
Nature:Synthetic,
Biochemical name:2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide,
Biological description:Potent, highly selective ATP non-competitive MEK1/2 inhibitor. Enhances cisplatin (ab141398) dependent apoptosis. Shows antitumor effects in vivo. Orally active.,
Canonical smiles:C1CC1CONC(=O)C2=C(C(=C(C=C2)F)F)NC3=C(C=C(C=C3)I)Cl,
InChi:InChI=1S/C17H14ClF2IN2O2/c18-12-7-10(21)3-6-14(12)22-16-11(4-5-13(19)15(16)20)17(24)23-25-8-9-1-2-9/h3-7,9,22H,1-2,8H2,(H,23,24),
InChiKey:GFMMXOIFOQCCGU-UHFFFAOYSA-N,
IUPAC Name:2-(2-chloro-4-iodoanilino)-N-(cyclopropylmethoxy)-3,4-difluorobenzamide

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store in the dark, Store under desiccating conditions, This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes