Abcam, ab165173, Recombinant Human OR10AD1 protein

Size: 2µg
Recombinant Human OR10AD1 protein is a Human Full Length protein, in the 1 to 317 aa range, expressed in Wheat germ, suitable for ELISA, WB.
Key facts
Expression system:Wheat germ,
Tags:GST tag N-Terminus,
Applications:WB, ELISASee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Biologically active:No,
Accession:Q8NGE0,
Animal free:No,
Carrier free:No,
Species:Human,
Storage buffer:pH: 8Constituents: 0.79% Tris HCl, 0.31% Glutathione

Properties and Storage Information:
Shipped at conditions-Dry Ice, Appropriate long-term storage conditions--80°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
OR10AD1 also known as Olfactory Receptor 10AD1 is a G-protein coupled receptor involved in olfactory signal transduction. It has a molecular mass of approximately 34 kDa. This olfactory receptor is expressed in the sensory neurons of the olfactory epithelium. OR10AD1 contributes to detecting specific odorant molecules helping to initiate smell perception.
Biological function summary
The olfactory receptor 10AD1 contributes to the detection of chemical stimuli necessary for olfactory perception. It forms part of a vast family of olfactory receptors which work collectively to identify a wide range of odorant molecules. It has a role in a sophisticated system that helps animals recognize food predators and mating partners based on scent.
Pathways
The olfactory transduction pathway involves OR10AD1 translating external chemical signals into neuronal responses. This receptor associates with the G-protein olfactory transduction cascade where it activates adenylate cyclase leading to the production of cAMP. It might relate to other olfactory receptors such as those activating similar signaling molecules like AC3 facilitating the detection of diverse odorants.
Researchers have not extensively linked OR10AD1 to specific pathologies. However olfactory receptors in general have potential implications in conditions like anosmia or the loss of smell which can affect the quality of life. Some studies explore their roles in neurological diseases due to their expression in brain regions beyond the olfactory epithelium where OR10AD1 could interact with other proteins like OMP (Olfactory Marker Protein).