Abcam, ab170885, Anti-ZNF92 antibody [EPR11514]

Size: 100µL / 1mL
Rabbit Recombinant Monoclonal ZNF92 antibody. Suitable for WB and reacts with Human samples. Cited in 1 publication.
Key facts
Host species:Rabbit,
Clonality:Monoclonal,
Clone number:EPR11514,
Isotype:IgG,
Carrier free:No,
Reacts with:Human,
Applications:WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:The exact immunogen used to generate this antibody is proprietary information.

Product details:
Patented technology
Our RabMAb
technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to
RabMAb® patents
What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:
- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production
For more information, read more on
recombinant antibodies

Properties and Storage Information:
Form-Liquid, Purity-Tissue culture supernatant, Storage buffer-pH: 7.2 - 7.4Preservative: 0.01% Sodium azideConstituents: PBS, 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 0.05% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
ZNF92 also known as Zinc Finger Protein 92 functions as a transcription factor binding to specific DNA sequences to regulate gene expression. ZNF92 contains a series of C2H2-type zinc finger domains which facilitate its DNA binding capabilities. The protein has an approximate molecular mass of 64 kDa. Researchers have noted its expression in various human tissues with significant levels in the brain and liver indicating roles in specific cellular contexts.
Biological function summary
The role of ZNF92 involves modulating transcription to influence cellular processes. It does not usually operate alone; instead it often participates in complexes with other transcription factors and co-regulators impacting the transcriptional landscape of genes under its control. By interacting with promoter regions ZNF92 can activate or repress certain genes contributing to the fine-tuning of cellular activities.
Pathways
ZNF92 integrates into key developmental and cellular differentiation pathways. It plays a part in the Wnt signaling pathway which is critical for cell proliferation differentiation and migration. ZNF92 also interacts with proteins such as β-catenin a central component of this pathway to modulate gene expression outcomes that are important for maintaining cellular functions and development.
Alterations in ZNF92 activity have been linked to neurological conditions and liver diseases. Aberrant expression or mutations of ZNF92 impact the normal regulatory functions in the brain associating it with disorders such as neurodevelopmental delays. Similarly its interactions with hepatocyte-related transcription factors suggest a role in liver pathologies. Dysregulation in these contexts can contribute to the onset and progression of these disorders highlighting its importance in maintaining tissue-specific health.