Abcam, ab180167, Anti-NUDT19 antibody [EPR13162-106]

Size: 100µL / 1mL
Rabbit Recombinant Monoclonal NUDT19 antibody. Suitable for WB, ICC/IF and reacts with Human samples. Cited in 1 publication.
Key facts
Host species:Rabbit,
Clonality:Monoclonal,
Clone number:EPR13162-106,
Isotype:IgG,
Carrier free:No,
Reacts with:Human,
Applications:ICC/IF, WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:The exact immunogen used to generate this antibody is proprietary information.

Product details:
Patented technology
Our RabMAb
technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to
RabMAb® patents
What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:
- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production
For more information, read more on
recombinant antibodies

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Protein A, Storage buffer-pH: 7.2 - 7.4Preservative: 0.01% Sodium azideConstituents: PBS, 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 0.05% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
NUDT19 also known as Diphosphatase NUDT19 is a protein that functions by hydrolyzing nucleoside diphosphates which are involved in various biochemical processes such as cell signaling and metabolism. It carries a molecular mass of approximately 22 kDa. NUDT19 mostly expresses in the kidneys and liver playing important roles in detoxification and energy metabolism in these tissues.
Biological function summary
NUDT19 is involved in regulating intracellular levels of Coenzyme A and its derivatives through its enzymatic action. By breaking down these molecules it helps maintain cellular metabolic balance. While it does not function as part of a larger complex its activity directly impacts the availability of metabolic substrates required for energy production and other cellular functions.
Pathways
NUDT19 plays a critical role in the Coenzyme A biosynthesis pathway. It contributes to the regulation of this pathway by controlling the levels of intermediates through its enzymatic activity. This protein links to other key enzymes such as ACSM3 which plays a part in the catabolism of fatty acids. These interactions highlight NUDT19’s involvement in lipid metabolism and energy balance.
NUDT19 has connections to metabolic disorders such as diabetes and fatty liver disease. Abnormal activity or expression of NUDT19 may lead to disruptions in energy metabolism contributing to the pathology of these conditions. Its role in managing Coenzyme A derivatives also ties it to SIRT5 a protein implicated in metabolic regulation and stress responses. Understanding NUDT19’s function could lead to insights into therapeutic strategies for related metabolic disorders.