Abcam, ab181214, Anti-PRMT7 antibody [EPR13495]

Size: 100µL / 1mL
Rabbit Recombinant Monoclonal PRMT7 antibody. Suitable for WB, ICC/IF and reacts with Human samples. Cited in 7 publications.
Key facts
Host species:Rabbit,
Clonality:Monoclonal,
Clone number:EPR13495,
Isotype:IgG,
Carrier free:No,
Reacts with:Human,
Applications:ICC/IF, WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:The exact immunogen used to generate this antibody is proprietary information.

Product details:
Patented technology
Our RabMAb
technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to
RabMAb® patents
What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:
- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production
For more information, read more on
recombinant antibodies

Properties and Storage Information:
Form-Liquid, Purity-Tissue culture supernatant, Storage buffer-Preservative: 0.01% Sodium azideConstituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
PRMT7 short for Protein Arginine Methyltransferase 7 plays an important role in the methylation of arginine residues on target proteins. It acts as a type of enzyme known for catalyzing the transfer of methyl groups. PRMT7 appears in several tissues although its expression is noted in higher amounts in brain and testis tissues. This protein weighs approximately 78 kDa and undergoes different modifications influencing its activity and localization. Researchers sometimes refer to PRMT7 simply as PRMT-7.
Biological function summary
The activity of this protein regulates gene expression by modifying histones and non-histone proteins affecting chromatin structure. It does not typically act as part of a large complex but can associate with other proteins to achieve specific functions. PRMT7 influences processes like protein signaling RNA processing and cell cycle control illustrating its diverse roles in cellular biology.
Pathways
PRMT7 participates intricately in pathways involving transcriptional regulation. It regulates pathways such as the arginine methylation pathway and is connected to transcription factor binding pathways. Its action intertwines with other methyltransferases and specific epigenetic regulators such as PRMT5 highlighting the crosstalk between different protein modification pathways within cells.
PRMT7 has a connection to cancer and neurodevelopmental disorders. Altered expression or activity of PRMT7 associates with oncogenesis making it a potential target in cancer research with some studies pointing out possible links to breast cancer. In neurodevelopmental disorders the protein's role in gene expression regulation suggests its involvement. In such conditions interactions with proteins such as FMR1 linked to Fragile X syndrome highlight the importance of understanding PRMT7's function to unravel its therapeutic implications.