Abcam, ab181384, Anti-C9orf167 antibody [EPR13193]

Size: 100µL / 1mL
Rabbit Recombinant Monoclonal C9orf167 antibody. Suitable for IP, WB and reacts with Human samples. Cited in 1 publication.
Key facts
Host species:Rabbit,
Clonality:Monoclonal,
Clone number:EPR13193,
Isotype:IgG,
Carrier free:No,
Reacts with:Human,
Applications:WB, IPSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:The exact immunogen used to generate this antibody is proprietary information.

Product details:
Patented technology
Our RabMAb
technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to
RabMAb® patents
What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:
- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production
For more information, read more on
recombinant antibodies

Properties and Storage Information:
Form-Liquid, Purity-Tissue culture supernatant, Storage buffer-pH: 7.2 - 7.4Preservative: 0.01% Sodium azideConstituents: PBS, 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 0.05% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
C9orf167 also known as neuron navigator 3 (NAV3) is a protein with a mass of approximately 189 kDa. It is part of the neuron navigator family. This protein exists in various tissues with high expression levels noted in the nervous system. C9orf167 plays a role in cytoskeletal dynamics and cellular processes involving actin and microtubules.
Biological function summary
C9orf167 influences cell morphology and motility by associating with elements that control the cytoskeleton. While it does not typically form part of a stable complex on its own it indirectly interacts with other proteins to mediate changes in cell structure. Its regulatory actions help guide axon pathfinding an essential process for neural network formation.
Pathways
C9orf167 contributes to the regulation of the Wnt signaling pathway and the axonal guidance pathway. This protein interacts with proteins like Dishevelled (related to the Wnt pathway) and also plays roles in the signaling pathways that direct growth cones in neurons ensuring correct neural circuit connections.
C9orf167 connections include roles in neurodevelopmental disorders and cancer. Alterations in its expression or function correlate with conditions such as autism alongside some cancer types like gliomas. In these contexts C9orf167 often interacts with proteins like PTEN which can influence tumor suppressive pathways and neural developmental processes.