Abcam, ab185473, Anti-ATPBD3 antibody

Size: 100µL
Rabbit Polyclonal ATPBD3 antibody. Suitable for IHC-P, ICC/IF and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Human CTU1 aa 50-200.
Key facts
Host species:Rabbit,
Clonality:Polyclonal,
Isotype:IgG,
Carrier free:No,
Reacts with:Human,
Applications:IHC-P, ICC/IFSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:Recombinant Fragment Protein within Human CTU1 aa 50-200. The exact immunogen used to generate this antibody is proprietary information.Q7Z7A3

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Immunogen, Storage buffer-pH: 7.2Preservative: 0.02% Sodium azideConstituents: PBS, 40% Glycerol (glycerin, glycerine), Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
ATPBD3 also known as ATP-binding domain 3 functions as an enzyme involved in energy metabolism. It possesses ATPase activity which allows it to hydrolyze ATP the energy currency of the cell. With a molecular mass of approximately 60 kDa ATPBD3 plays a significant role in cellular energy management. This protein is widely expressed in numerous tissues indicating its importance in diverse cellular activities. Cells harness ATPBD3's energy-converting abilities to sustain various metabolic processes critical for cell viability and function.
Biological function summary
ATPBD3 facilitates energy homeostasis and cellular metabolic processes. It performs as part of a complex that coordinates multiple cellular activities ensuring efficient energy production and utilization. This precise management of cellular energy resources is important for supporting cell survival promoting cell growth and regulating apoptosis. Through these activities ATPBD3 contributes significantly to maintaining cellular homeostasis and responding to metabolic demands.
Pathways
ATPBD3 integrates into cellular energy metabolism and stress response pathways. It engages in ATP synthesis and hydrolysis processes critical for energy production and cellular adaptation. The protein functions alongside other metabolic enzymes like AMP-activated protein kinase (AMPK) which senses cellular energy status and regulates metabolic pathways. ATPBD3's role in these pathways showcases its involvement in cellular responses to energy fluctuations aiding cells in adapting to metabolic shifts.
Faulty regulation or expression of ATPBD3 associates with metabolic disorders such as obesity and type 2 diabetes. Abnormalities in ATPBD3 function can disrupt energy balance leading to metabolic imbalances linked to these conditions. Additionally ATPBD3 interactions with proteins such as AMPK highlight its potential influence on glucose metabolism and insulin signaling pathways which are dysregulated in metabolic diseases. Investigating ATPBD3's role and interactions may offer insights into novel therapeutic strategies for addressing these metabolic challenges.