Abcam, ab187971, Anti-PDXDC1 antibody

Size: 100µL
Rabbit Polyclonal PDXDC1 antibody. Suitable for IHC-P, WB, ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human PDXDC1 aa 1-100.
Key facts
Host species:Rabbit,
Clonality:Polyclonal,
Isotype:IgG,
Carrier free:No,
Reacts with:Human,
Applications:ICC/IF, IHC-P, WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:Recombinant Fragment Protein within Human PDXDC1 aa 1-100. The exact immunogen used to generate this antibody is proprietary information.Q6P996

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Immunogen, Storage buffer-pH: 7.2Preservative: 0.02% Sodium azideConstituents: PBS, 40% Glycerol (glycerin, glycerine), Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
PDXDC1 also known as pyridoxal-dependent decarboxylase domain containing 1 functions as an enzyme involved in amino acid metabolism. This protein has a molecular mass of approximately 57 kDa. It is expressed in various tissues including liver kidney and muscle. PDXDC1 contains domains that suggest it may play a role in pyridoxal phosphate-dependent enzymatic reactions which are essential for certain metabolic processes.
Biological function summary
The activity of pyridoxal phosphate enzymes influences the synthesis and degradation of amino acids. PDXDC1 may form part of a larger enzymatic complex that facilitates these pathways ensuring cellular processes maintain proper amino acid levels. By participating in these reactions PDXDC1 helps cellular metabolism leading to the production of important metabolic intermediates required for energy balance and synthesis of biomolecules.
Pathways
Amino acid metabolism and its interconnections are influenced by PDXDC1. This protein interacts with pivotal pathways like the urea cycle and gluconeogenesis affecting energy production and nitrogen disposal. PDXDC1 has possible interactions with related proteins such as alanine aminotransferase which collaborates in the transamination and disposal of nitrogen.
Aberrant expression or mutation of PDXDC1 may connect to metabolic disorders and liver diseases. Metabolic imbalance involving amino acid metabolism potentially links PDXDC1 to liver dysfunction and metabolic syndrome. In disease conditions PDXDC1 may associate with proteins like glutamate dehydrogenase which plays a role in amino acid catabolism influencing the progression or management of related disorders.