Abcam, ab190267, Anti-SIX6OS1 antibody

Size: 100µL
Rabbit Polyclonal SIX6OS1 antibody. Suitable for IHC-P, ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human SIX6OS1 aa 200-300.
Key facts
Host species:Rabbit,
Clonality:Polyclonal,
Isotype:IgG,
Carrier free:No,
Reacts with:Human,
Applications:IHC-P, ICC/IFSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:Recombinant Fragment Protein within Human SIX6OS1 aa 200-300. The exact immunogen used to generate this antibody is proprietary information.Q8N1H7

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Immunogen, Storage buffer-pH: 7.2Preservative: 0.02% Sodium azideConstituents: PBS, 40% Glycerol (glycerin, glycerine), Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
SIX6OS1 also referred to as Six6 opposite strand RNA 1 is a protein involved in various cellular processes. It has a molecular weight of approximately 91 kDa. Expression of SIX6OS1 occurs mostly in tissues like the testis and ovary highlighting its significance in reproductive biology. The protein plays an important part in the regulation of gene expression through interaction with other cellular proteins.
Biological function summary
SIX6OS1 participates in the formation of ribonucleoprotein complexes important for RNA processing and stability. It operates as part of a complex involved in transcriptional regulation influencing the expression of target genes essential for cell cycle progression and differentiation. By interacting with several proteins SIX6OS1 maintains cellular homeostasis and contributes to the integrity of gene expression networks necessary for proper cell function.
Pathways
SIX6OS1 plays a role in the Wnt signaling and cell cycle pathways. It interacts with associated proteins such as beta-catenin participating actively in signal transduction processes that influence gene expression. Through its involvement in these pathways SIX6OS1 ensures that cells respond appropriately to external and internal signals facilitating coordinated responses necessary for balanced cell proliferation and differentiation.
Alterations in SIX6OS1 expression are associated with specific conditions like gonadal dysgenesis and certain forms of infertility. Changes in the levels or activity of SIX6OS1 may disrupt normal gonadal function linked to the action of associated proteins like CREBBP. Variations in these proteins can result in impaired reproductive capability demonstrating the need to understand molecular interactions involving SIX6OS1 in the context of reproductive health.