Abcam, ab19161, Anti-Cat Albumin antibody

Size: 1mg
Goat Polyclonal Albumin antibody. Suitable for ICC, ELISA, WB and reacts with Cat samples. Cited in 1 publication. Immunogen corresponding to Full Length Protein corresponding to Cat Albumin.
Key facts
Host species:Goat,
Clonality:Polyclonal,
Isotype:IgG,
Carrier free:No,
Reacts with:Cat,
Applications:ICC, ELISA, WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:Full Length Protein corresponding to Cat Albumin. The exact immunogen used to generate this antibody is proprietary information.P49064

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Immunogen, Storage buffer-pH: 6.8 - 7.4Preservative: 0.1% Sodium azideConstituents: PBS, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
Cat Albumin often referred to as feline albumin is a major protein found in the bloodstream of cats with a molecular mass of approximately 66.5 kDa. It is synthesized in the liver and represents a large proportion of the total serum protein content. This protein plays an important role in maintaining osmotic pressure and balancing fluid distribution between body compartments. In addition to its function in serum cat albumin also appears in other physiological fluids such as urine lymph and cerebrospinal fluid.
Biological function summary
The transport capabilities of cat albumin make it significant for binding and moving various substances including hormones drugs and fatty acids. This protein doesn’t operate as part of a complex but exhibits strong binding sites for molecules allowing it to regulate the availability and solubility of bioactive compounds. This regulation is essential for metabolic processes and pharmacokinetics impacting how substances transfer throughout the feline body. Its interaction with numerous ligands enhances its role in detoxification and nutrient distribution.
Pathways
Albumin in cats functions notably within the circulatory system and homeostatic pathways. It interacts with proteins such as α1-acid glycoprotein and transferrin. This interaction is important for iron regulation and acute phase response. Cat albumin helps in maintaining blood pH and acting as a buffer by binding hydrogen ions. This buffering capability supports catabolic and anabolic processes vital for maintaining equilibrium under various conditions including stress and inflammation.
Alterations in the levels of cat albumin connect to conditions like kidney disease and liver cirrhosis. In chronic kidney disease cat albumin levels often reduce leading to complications such as edema and fluid imbalance. The reduction closely ties with damage to glomerular structures where cat albumin leakage can occur. In liver disorders the synthesis of albumin can decrease highlighting its significance in hepatic function. Cellular proteins like globulins and fibrinogen are commonly affected alongside albumin reflecting changes in blood composition during these diseases.