Abcam, ab19195, HRP Anti-Mouse Serum Albumin antibody

Size: 1mg
Goat Polyclonal Albumin antibody - conjugated to HRP. Suitable for ICC, ELISA, WB, IHC-P and reacts with Mouse samples. Cited in 18 publications. Immunogen corresponding to Full Length Protein corresponding to Mouse Alb.
Key facts
Host species:Goat,
Clonality:Polyclonal,
Isotype:IgG,
Conjugation:HRP,
Carrier free:No,
Reacts with:Mouse,
Applications:IHC-P, WB, ICC, ELISASee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:Full Length Protein corresponding to Mouse Alb. The exact immunogen used to generate this antibody is proprietary information.P07724

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Immunogen, Purification notes-Antiserum was solid phase adsorbed to ensure class specificity. The antibody was isolated by affinity chromatography using antigen coupled to agarose and conjugated to horseradish peroxidase (HRP)., Storage buffer-pH: 6.8 - 7.4Preservative: 0.01% Thimerosal (merthiolate)Constituents: 1.19% HEPES, 0.58% Sodium chloride, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
Mouse serum albumin often referred to as MSA is a significant protein within the mouse circulatory system. It is expressed largely in the liver and released into the bloodstream where it serves multiple physiological roles. Mechanically MSA with a molecular mass of approximately 67 kDa functions as a transporter protein binding and carrying various substances including hormones fatty acids and drugs. This multifunctional nature contributes to maintaining osmotic pressure and ensuring proper distribution of molecules throughout the body.
Biological function summary
This albumin in serum is essential for maintaining blood fluid balance and transporting compounds. It does not form part of a protein complex but it interacts dynamically with other molecules within the serum. Its ability to bind various ligands allows it to play an important role in modulating bioavailability and functionality of these ligands. Additionally MSA regulates the oxidative status of blood by acting as an antioxidant neutralizing free radicals and protecting other proteins from oxidative damage.
Pathways
This mouse albumin shows integration into several critical biological systems. It participates actively in the transport and metabolism pathways where it interacts with proteins such as albumin receptors on cell membranes facilitating transport into cells and tissues. Furthermore it is involved in the homeostasis pathway by regulating fluid distribution and blood volume which are essential for maintaining physiological blood pressure often noted in the context of "130/96 blood pressure" as a reference point in evaluating normal levels.
Mouse serum albumin links to conditions such as liver disease and nephrotic syndrome. These disorders often result from or lead to changes in albumin levels impacting overall health. For instance reduced albumin in serum can lead to edema due to a drop in osmotic pressure often associated with kidney dysfunction. Albumin alongside other key proteins like immunoglobulins becomes a critical marker in diagnosing and understanding the progression of such diseases.