Abcam, ab195313, Anti-C6orf106 antibody

Size: 100µg
Rabbit Polyclonal C6orf106 antibody. Suitable for IP, WB and reacts with Human, Mouse samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human ILRUN aa 200 to C-terminus.
Key facts
Host species:Rabbit,
Clonality:Polyclonal,
Isotype:IgG,
Carrier free:No,
Reacts with:Mouse, Human,
Applications:IP, WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:Synthetic Peptide within Human ILRUN aa 200 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.Q9H6K1

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Immunogen, Storage buffer-pH: 7 - 8Preservative: 0.09% Sodium azideConstituents: 99% Tris citrate/phosphate, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
C6orf106 also known as Chromosome 6 Open Reading Frame 106 is a protein whose precise mechanical function is still undergoing research. It has an approximate molecular mass of 24 kDa. Scientists have observed its expression widely across various tissues with notable presence in the immune system suggesting an important role in immune responses. Although investigations into its complete roles are ongoing C6orf106 is gaining attention due to its potential significance in cellular processes.
Biological function summary
C6orf106 influences gene regulation and immune function. The protein interacts with several partners within the cell although concrete details about a specific complex are yet to be confirmed. Its expression patterns suggest it may play a role in cellular communication and signaling processes. Current research indicates that C6orf106 possibly interacts with pathways that involve transcriptional regulation which highlights its importance in controlling cellular activities that impact broader system functions such as immunity.
Pathways
C6orf106 becomes active in those related to immune system signaling and transcriptional regulation. Notable pathways include the JAK-STAT signaling pathway essential in transmitting information from extracellular signals to the nucleus and potentially the NF-kB pathway known for its role in inflammatory responses. Links to key proteins such as STAT3 in these pathways indicate that C6orf106 could influence important regulatory mechanisms that maintain immune homeostasis and response.
C6orf106 has connections with immune-related conditions and autoimmune diseases. Research suggests potential links to rheumatoid arthritis where its role in immune signaling may contribute to inflammation and joint damage. There is also an interest in its association with chronic inflammatory conditions. Investigations explore its interactions with proteins like TNF-alpha as these connections might provide insights into how C6orf106 may influence disease progression and severity. Understanding these relationships is critical to potentially developing targeted therapies in the future.