Abcam, ab205302, Anti-ATHL1 antibody [EPR13421]

Size: 100µL / 1mL
Rabbit Recombinant Monoclonal ATHL1 antibody. Suitable for WB, ICC/IF and reacts with Human samples. Cited in 1 publication.
Key facts
Host species:Rabbit,
Clonality:Monoclonal,
Clone number:EPR13421,
Isotype:IgG,
Carrier free:No,
Reacts with:Human,
Applications:WB, ICC/IFSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:The exact immunogen used to generate this antibody is proprietary information.

Product details:
Patented technology
Our RabMAb
technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to
RabMAb® patents
What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:
- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production
For more information, read more on
recombinant antibodies

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Protein A, Storage buffer-pH: 7.2 - 7.4Preservative: 0.01% Sodium azideConstituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
ATHL1 also known as ATHL1 protein is a protein with a molecular weight of approximately 70 kDa. Known to be expressed largely in the human brain ATHL1 plays a role in various cellular functions. It is found distributed in other tissues as well but with lower levels noted. This protein interacts with cellular pathways and processes helping in the regulation of key molecular functions.
Biological function summary
ATHL1 engages with cytoskeletal elements and impact cellular structure and stability. It does not form part of a larger protein complex but acts through a collaborative network with other proteins. Its interactions support various cellular processes by influencing the components involved in maintaining cellular shape and integrity. ATHL1's role in these processes makes it an important element in the understanding of cellular dynamics.
Pathways
ATHL1 gets involved in the regulation of the MAPK/ERK pathway. It links with critical components like ERK1/2 affecting cell growth and survival. Another significant pathway involving ATHL1 is the Wnt signaling pathway. This pathway important for numerous developmental processes sees ATHL1 contributing to cellular signaling cascades that determine cell fate and proliferation.
ATHL1 has links to neurological conditions notably Alzheimer's disease. It potentially interacts with tau protein which is known for its role in neurodegenerative processes. Additionally ATHL1's involvement in cellular structural integrity suggests potential ties to cancer where disruptions in cell framework can lead to malignant transformations. Its connections with cytoskeletal proteins highlight ATHL1's role in disease mechanisms and offer avenues for therapeutic exploration.