Abcam, ab220973, Anti-DIP2C antibody

Size: 100µL
Rabbit Polyclonal DIP2C antibody. Suitable for WB, ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human DIP2C aa 1-100.
Key facts
Host species:Rabbit,
Clonality:Polyclonal,
Isotype:IgG,
Carrier free:No,
Reacts with:Human,
Applications:ICC/IF, WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:Recombinant Fragment Protein within Human DIP2C aa 1-100. The exact immunogen used to generate this antibody is proprietary information.Q9Y2E4

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Immunogen, Storage buffer-pH: 7.2Preservative: 0.02% Sodium azideConstituents: PBS, 40% Glycerol (glycerin, glycerine), Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
DIP2C also known as Disco Interacting Protein 2 Homolog C acts as a protein with a role in cellular processes. It has a molecular mass of approximately 161 kDa. Researchers have detected its expression in various tissues including the brain heart and skeletal muscle. DIP2C shows involvement in cellular signaling and structural functions allowing it to carry out complex actions within the cell.
Biological function summary
Scientists recognize DIP2C as an important element in neural development and synaptic plasticity. It functions actively in cellular communication and may exist as part of a larger molecular complex involved in transmitting signals necessary for maintaining cellular health and development. By interacting with other proteins DIP2C supports structural integrity and functionality of neural circuits impacting learning and memory.
Pathways
Scientists know that DIP2C plays a role in both the Wnt signaling and receptor tyrosine kinase pathways. These pathways remain essential for cell fate determination and proliferation. DIP2C interacts with other proteins like β-catenin in the Wnt pathway aiding in the regulation of gene expression that contributes to cellular growth and development.
DIP2C has connections to neurodevelopmental disorders and some cancers. Researchers observed that altered expression of DIP2C could link to autism spectrum disorders affecting neural communication and information processing in the brain. Furthermore DIP2C relates to oncogenic pathways where its interaction with proteins like MYC can contribute to tumorigenesis suggesting a possible role in cancer development and progression.