Abcam, ab222839, Anti-C6ORF10 antibody

Size: 50µL
Rabbit Polyclonal C6ORF10 antibody. Suitable for WB, IHC-P, ICC/IF and reacts with Mouse, Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human TSBP1 aa 200-500.
Key facts
Host species:Rabbit,
Clonality:Polyclonal,
Isotype:IgG,
Carrier free:No,
Reacts with:Mouse, Human,
Applications:IHC-P, WB, ICC/IFSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:Recombinant Fragment Protein within Human TSBP1 aa 200-500. The exact immunogen used to generate this antibody is proprietary information.Q5SRN2

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Protein G, Purification notes-Purity >95%, Storage buffer-pH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine), Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
C6ORF10 also known as Chromosome 6 Open Reading Frame 10 is a protein whose function remains largely uncharacterized. It has an approximate molecular mass of 24 kDa. This protein exhibits expression in various tissues with noteworthy levels in immune-related organs such as the spleen and lymph nodes. Despite lacking a detailed functional profile studies suggest its involvement in immune system processes.
Biological function summary
C6ORF10 appears to play a role in cellular immune responses. It is associated with a complex known to include several proteins involved in immune regulation though specific components of this complex largely remain under investigation. This suggests that C6ORF10 might assist in signaling or regulatory roles within some immune pathways.
Pathways
C6ORF10 may participate in the antigen processing and presentation pathway a critical element of the immune response. It seems to work alongside other proteins like MHC class I molecules in presenting antigens to the immune system. Furthermore it may also have connections to the interferon signaling pathway collaborating with proteins such as STAT1 to modulate responses to pathogens.
C6ORF10 shows potential links to autoimmune diseases like rheumatoid arthritis. Malfunction or dysregulation of C6ORF10 in conjunction with proteins such as interleukin-6 could contribute to inflammatory processes central to the disease's pathology. Additionally preliminary evidence also suggests a possible involvement in certain cancer types wherein its role in immune modulation may impact tumor immunity dynamics.