Abcam, ab224036, Anti-Apolipoprotein O like antibody

Size: 100µL
Rabbit Polyclonal Apolipoprotein O like antibody. Suitable for IHC-P, WB, ICC/IF and reacts with Human, Mouse, Rat samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human APOOL aa 100 to C-terminus.
Key facts
Host species:Rabbit,
Clonality:Polyclonal,
Isotype:IgG,
Carrier free:No,
Reacts with:Mouse, Rat, Human,
Applications:WB, ICC/IF, IHC-PSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:Recombinant Fragment Protein within Human APOOL aa 100 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.Q6UXV4

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Immunogen, Storage buffer-pH: 7.2Preservative: 0.02% Sodium azideConstituents: PBS, 40% Glycerol (glycerin, glycerine), Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
Apolipoprotein O-like sometimes known simply as ApoOL plays a role in lipid metabolism. This protein has a mass of approximately 22 kDa and is expressed in various tissues including the liver and intestines which are vital for lipid processing. It contributes to the regulation of lipid transport and availability in cells interacting with lipid-containing particles such as lipoproteins.
Biological function summary
Apolipoprotein O-like influences lipid homeostasis and energy metabolism within the body. It does not function as a part of a larger complex but still interacts with other proteins involved in lipid regulation. Its role in the body involves maintaining proper lipid levels and ensuring energy is properly stored and utilized especially in tissues relying on lipids as an energy source.
Pathways
Apolipoprotein O-like is involved in the lipid metabolic pathway an essential process for maintaining cellular membrane integrity and energy storage. In this pathway it relates to other proteins like Apolipoprotein E which is critical for lipid transport and redistribution. ApoOL's function contributes to the overall balance of lipid levels across different cell types ensuring metabolic needs are met consistently and efficiently.
Apolipoprotein O-like shows connections to conditions such as dyslipidemia and cardiovascular disease. Changes in its expression or function may alter lipid levels implicating it in the development of these conditions. In the context of cardiovascular disease ApoOL's interactions with proteins like Apolipoprotein B suggest its contribution to lipid abnormalities that influence heart health.