Abcam, ab228707, Anti-CXorf57 antibody

Size: 100µL
Rabbit Polyclonal CXorf57 antibody. Suitable for WB, ICC/IF and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Human RADX.
Key facts
Host species:Rabbit,
Clonality:Polyclonal,
Isotype:IgG,
Carrier free:No,
Reacts with:Human,
Applications:WB, ICC/IFSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:Recombinant Fragment Protein within Human RADX. The exact immunogen used to generate this antibody is proprietary information.Q6NSI4

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Immunogen, Storage buffer-pH: 7Preservative: 0.01% Thimerosal (merthiolate)Constituents: 20% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
CXorf57 also known as chromosome X open reading frame 57 is a protein encoded by the CXorf57 gene located on the X chromosome. The protein has a mass of approximately 26 kDa. It is expressed in various tissues with notable expression in the central nervous system including brain regions involved in cognitive functions. CXorf57 does not belong to any well-characterized family of proteins and remains an intriguing target for further functional elucidation.
Biological function summary
CXorf57 participates in cellular processes by acting as a regulatory protein. It does not form part of any known protein complexes but its role suggests involvement in transcriptional control. Researchers hypothesize that CXorf57 may have interactions with nuclear components due to its expression patterns and regulatory functions. Further functional studies are needed to detail the specific biological activities and interactions of CXorf57.
Pathways
CXorf57 intersects with signaling and developmental processes indicating a possible role in neural development pathways. Evidence suggests links to the PI3K-Akt pathway which involves proteins like Akt1 and is important for cell survival and growth. Such pathways are important for understanding how CXorf57 may influence cellular homeostasis and neuronal function.
CXorf57 has potential associations with neurological conditions such as intellectual disability and autism spectrum disorder. Alterations in CXorf57 expression or function could disrupt neuronal signaling contributing to these disorders. Interactions with proteins like MeCP2 have been noted which is relevant in the context of Rett syndrome and highlights the importance of understanding CXorf57 in neurodevelopmental disease contexts. Future research should aim to elucidate the precise mechanistic roles CXorf57 plays in these disease pathways.