Abcam, ab240116, Anti-Integrin alpha 9 antibody [EPR9722] - BSA and Azide free

Size: 100µg / 1mg
Rabbit Recombinant Monoclonal Integrin alpha 9 antibody. Carrier free. Suitable for IHC-P, WB and reacts with Human, Mouse, Rat samples. Cited in 2 publications.
Key facts
Host species:Rabbit,
Clonality:Monoclonal,
Clone number:EPR9722,
Isotype:IgG,
Carrier free:Yes,
Reacts with:Mouse, Human,
Applications:IHC-P, WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:The exact immunogen used to generate this antibody is proprietary information.

Product details:
ab240116 is the carrier-free version of
ab140599
Patented technology
Our RabMAb
technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to
RabMAb® patents
What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:
- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production
For more information, read more on
recombinant antibodies
Conjugation ready
Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.
Use our
conjugation kits
for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.
Compatibility
This product is compatible with the Maxpar
Antibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar
is a trademark of Fluidigm Canada Inc.

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Protein A, Storage buffer-pH: 7.2 - 7.4Constituents: PBS, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-Do Not Freeze

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
Integrin alpha 9 also known as alpha-nine or alpha-9 is a transmembrane protein that is part of the integrin family. It typically forms dimer with beta-1 integrin subunit. This protein has an approximate mass of 150 kDa. Integrin alpha 9 is expressed in various tissues with notable levels in the epithelial cells smooth muscle cells and leukocytes. Its primary mechanical role involves mediating cell adhesion and signaling by interacting with the extracellular matrix (ECM) components and some specific ligands.
Biological function summary
Integrin alpha 9 influences cell migration proliferation and survival through its interactions with ECM proteins like tenascin-C and osteopontin. It does not function alone; it forms part of a complex that includes various signaling molecules and cytoskeletal proteins. These associations facilitate communication between the cell cytoskeleton and the ECM influencing processes like wound healing and inflammation.
Pathways
Integrin alpha 9 plays roles in pathways such as the integrin signaling pathway and the focal adhesion pathway. It interacts closely with molecules like focal adhesion kinase (FAK) and Paxillin which are critical within these pathways. These relationships allow integrin alpha 9 to modulate cellular responses such as spreading migration and cellular structural organization.
Integrin alpha 9 has connections with conditions such as asthma and cancer. In asthma its interaction with ECM proteins contributes to inflammation and airway remodeling. In cancer altered expression and signaling through integrin alpha 9 can influence tumor growth and metastasis. The protein's involvement in disease processes often interacts with other integrins and receptors that regulate inflammation and cellular migration such as certain cytokine receptors.