Abcam, ab248936, Anti-RBMS1 antibody [EPR9825(B)] - BSA and Azide free

Size: 100µg / 1mg
Rabbit Recombinant Monoclonal RBMS1 antibody. Carrier free. Suitable for WB and reacts with Human, Rat, Mouse samples. Cited in 1 publication.
Key facts
Host species:Rabbit,
Clonality:Monoclonal,
Clone number:EPR9825(B),
Isotype:IgG,
Carrier free:Yes,
Reacts with:Mouse, Rat, Human,
Applications:WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:The exact immunogen used to generate this antibody is proprietary information.

Product details:
ab248936 is the carrier-free version of
ab150353
Patented technology
Our RabMAb
technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to
RabMAb® patents
What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:
- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production
For more information, read more on
recombinant antibodies
Conjugation ready
Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.
Use our
conjugation kits
for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.
Compatibility
This product is compatible with the Maxpar
Antibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar
is a trademark of Fluidigm Canada Inc.

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification, Storage buffer-pH: 7.2 - 7.4Constituents: PBS, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-Do Not Freeze

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
RBMS1 or RNA-binding motif single-stranded interacting protein 1 is a protein that plays an important role in binding single-stranded RNA and DNA. It has a molecular mass of approximately 45 kDa and is widely expressed in various tissues including but not limited to the brain liver and heart. Functionally RBMS1 contributes to a range of cellular processes by regulating the stability and translation of its bound nucleic acids.
Biological function summary
The RNA-binding capabilities of RBMS1 enable it to exert influence over gene expression and cellular proliferation. RBMS1 interacts with multiple other proteins becoming part of larger complexes that facilitate its regulatory actions. Complex formation with diverse molecular partners allows RBMS1 to influence different aspects of RNA metabolism and stability impacting cellular growth and development.
Pathways
The involvement of RBMS1 is notable in pathways regulating cell cycle and apoptosis. RBMS1 associates with components of the cell cycle control machinery affecting checkpoint regulation and cell proliferation. Its interaction with proteins like MYC and other cell cycle pathogenic elements highlights its role in the fine-tuning of growth-related cascades and programmed cell death mechanisms.
RBMS1 is associated with certain types of cancer notably those where gene expression misregulation is a factor. Altered expression or mutation of RBMS1 may contribute to oncogenic processes alongside proteins such as KRAS facilitating tumor progression and metastasis. Furthermore RBMS1 dysregulation can influence neurological disorders possibly through pathways that involve cell death such as those linked to neurodegenerative disease markers.