Abcam, ab250256, Anti-AWP1 antibody [EPR12323] - BSA and Azide free

Size: 100µg / 1mg
Rabbit Recombinant Monoclonal AWP1 antibody. Carrier free. Suitable for WB, Flow Cyt (Intra) and reacts with Human samples. Cited in 1 publication.
Key facts
Host species:Rabbit,
Clonality:Monoclonal,
Clone number:EPR12323,
Isotype:IgG,
Carrier free:Yes,
Reacts with:Human,
Applications:WB, Flow Cyt (Intra)See reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:The exact immunogen used to generate this antibody is proprietary information.

Product details:
ab250256 is the carrier-free version of
ab180856
Patented technology
Our RabMAb
technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to
RabMAb® patents
What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:
- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production
For more information, read more on
recombinant antibodies
Conjugation ready
Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.
Use our
conjugation kits
for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.
Compatibility
This product is compatible with the Maxpar
Antibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar
is a trademark of Fluidigm Canada Inc.

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification, Storage buffer-pH: 7.2 - 7.4Constituents: PBS, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-Do Not Freeze

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
AWP1 also known as AWP1 or AWP1 protein functions mechanically as an adapter molecule involved in various cellular processes. This protein is approximately 36 kDa in mass. AWP1 is expressed throughout many tissues including the heart liver and kidney. Its expression reflects the diverse roles it plays across different cellular environments where it modulates interactions between proteins.
Biological function summary
AWP1 participates in the regulation of signaling pathways and cellular communication. It acts as part of a protein complex that facilitates the interaction between membrane proteins and cytosolic components. AWP1's role in modulating these interactions is important for maintaining normal cellular activities impacting processes such as cell proliferation and apoptosis.
Pathways
AWP1 plays roles in the signaling and immune pathways. It influences the NF-kB signaling pathway an important pathway involved in immune response and inflammation. AWP1 interacts with proteins like TRAF6 impacting the cascade of signaling events that regulate cellular responses to external stimuli. Additionally it participates in pathways related to cellular stress responses integrating signals that dictate cell survival.
AWP1 associates with conditions like inflammation and cancer. In certain cancers dysregulated AWP1 expression is connected to abnormal cell proliferation and survival. The protein interacts with other key players like PI3K which contribute to oncogenic processes in cancer. In inflammatory disorders AWP1's role in modulating NF-kB signaling can lead to altered immune responses potentially exacerbating disease severity.