Abcam, ab273383, P 22077

Size: 10mg / 50mg
MW 315.3 Da, Purity >98%. Selective USP7 (IC 50 = 8 μM) inhibitor. Active against closely related USP47. Selective versus SENP2c0re (IC 50 >50 μM) and DENI (IC 50 >50 μM). Destabilizes Claspin. Inhibits neuroblastoma growth by inducing p53-mediated apoptosis. Inhibits Tip60 deubiquitination.
Key facts
CAS number:1247819-59-5,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:315.3 Da,
Molecular formula:C12H7F2NO3S2,
PubChem:46931953,
Nature:Synthetic,
Solubility:Soluble in DMSO to 75 mM,
Biochemical name:1-[5-(2,4-Difluoro-phenylsulfanyl)-4-nitro-thiophen-2-yl]-ethanone,
Biological description:Selective USP7 (IC50 = 8 μM) inhibitor. Active against closely related USP47. Selective versus SENP2c0re (IC50 >50 μM) and DENI (IC50 >50 μM). Destabilizes Claspin. Inhibits neuroblastoma growth by inducing p53-mediated apoptosis. Inhibits Tip60 deubiquitination.,
Canonical smiles:CC(=O)C1=CC(=C(S1)SC2=C(C=C(C=C2)F)F)[N+](=O)[O-],
InChi:InChI=1S/C12H7F2NO3S2/c1-6(16)11-5-9(15(17)18)12(20-11)19-10-3-2-7(13)4-8(10)14/h2-5H,1H3,
InChiKey:RMAMGGNACJHXHO-UHFFFAOYSA-N,
IUPAC Name:1-[5-(2,4-difluorophenyl)sulfanyl-4-nitrothiophen-2-yl]ethanone

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions