Abcam, ab275923, Tetracycline 10-O-β-D-galactopyranoside

Size: 2mg
MW 606.6 Da. Broad spectrum polyketide antibiotic. Produced by Streptomyces genus of Actinobacteria. Acts as a protein synthesis inhibitor and is commonly used to treat acne today, and, more recently, rosacea. Historically important in reducing the number of deaths from cholera. In this galactoside analog, upon enzymatic or chemical hydrolysis of the galactoside group, the active antibiotic tetracyline is produced.
Key facts
CAS number:319426-63-6,
Form:SolidSee storage information,
Molecular weight:606.6 Da,
Molecular formula:C28H34N2O13,
PubChem:54730589,
Nature:Synthetic,
Solubility:Soluble in DMSOSoluble in water,
Biochemical name:Tetracycline 10-O-B-D-galactopyranoside,
Biological description:Broad spectrum polyketide antibiotic. Produced by Streptomyces genus of Actinobacteria. Acts as a protein synthesis inhibitor and is commonly used to treat acne today, and, more recently, rosacea. Historically important in reducing the number of deaths from cholera. In this galactoside analog, upon enzymatic or chemical hydrolysis of the galactoside group, the active antibiotic tetracyline is produced.,
Canonical smiles:CC1(C2CC3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4OC5C(C(C(C(O5)CO)O)O)O)O)O)O)C(=O)N)N(C)C)O,
Isomeric smiles:C[C@@]1([C@H]2C[C@H]3[C@@H](C(=O)C(=C([C@]3(C(=O)C2=C(C4=C1C=CC=C4O[C@H]5[C@@H]([C@H]([C@H]([C@H](O5)CO)O)O)O)O)O)O)C(=O)N)N(C)C)O,
InChi:InChI=1S/C28H34N2O13/c1-27(40)9-5-4-6-12(42-26-22(36)21(35)18(32)13(8-31)43-26)14(9)19(33)15-10(27)7-11-17(30(2)3)20(34)16(25(29)39)24(38)28(11,41)23(15)37/h4-6,10-11,13,17-18,21-22,26,31-33,35-36,38,40-41H,7-8H2,1-3H3,(H2,29,39)/t10-,11-,13+,17-,18-,21-,22+,26+,27+,28-/m0/s1,
InChiKey:NQIGPCCKIYYEBO-UCUSNPRGSA-N,
IUPAC Name:(4S,4aS,5aS,6S,12aR)-4-(dimethylamino)-1,6,11,12a-tetrahydroxy-6-methyl-3,12-dioxo-10-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4,4a,5,5a-tetrahydrotetracene-2-carboxamide

Product details:
Naleway J, Howard R. (2001) 'Compositions and methods for targeted enzymic release of cell regulatory compounds.' PCT Int. Appl. (2001), WO 2001002020 A2.
Naleway JJ, Howard RA. (2006) 'Compositions and methods for the preparation of glycosides targeted enzymic release of cell regulatory compounds.'U.S. Pat. Appl. Publ. (2006), US 20060105915 A1.

Properties and Storage Information:
Shipped at conditions-Blue Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions