Abcam, ab284177, PRC Pathway Modulator Set

Size: 1Kit
PRC Pathway Modulator Set (ab284177) is part of the multiplex kits range. Abcam offers high-quality biological reagents and tools including antibodies, proteins, assays, cell lines and lysates.
Product details:
A convenient set containing 6 ready-to-use Polycomb inhibitors and activators. The set comprises high-purity compounds carefully chosen for their selectivity and potency, providing the perfect tool to study Polycomb-group proteins function and PcG related pathways. All compounds are provided in screw-cap vials, already dissolved in DMSO at a 10 mM concentration. Compounds in DMSO solution may precipitate out of solution when stored at reduced temperatures. Before use, make sure all vials have warmed to room temperature. Please examine all vials to ensure that all material has redissolved – slight warming and/or sonication may be required.
The set contains:
DZNep - Selective lysine methyltransferase EZH2 (KMT63) inhibitor
EED-226 - Potent, selective PRC2 inhibitor
PRT4165 - Potent inhibitor of PRC1 - mediated histone H2A ubiquitylation
PTC209 - BMI-1 inhibitor
Tazemetostat - Potent, selective histone methyltransferase EZH2 inhibitor
UNC3866 - Potent, selective antagonist of CBX4 and CBX7 chromodomains

Properties and Storage Information:
Shipped at conditions-Blue Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information--20°C