Product Description
Size: 5mg / 25mg
MW 460.5 Da, Purity >98%. Ppotent PDE4 (phosphodiesterase 4) inhibitor (IC₅₀ = 74 nM). It reduces TNF-α production in human synovial cells and significantly suppresses experimental arthritis.
Key facts
CAS number:608141-41-9,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:460.5 Da,
Molecular formula:C22H24N2O7S,
PubChem:11561674,
Nature:Synthetic,
Solubility:DMSO (>80 mg/ml),
Biochemical name:Apremilast,
Biological description:Ppotent PDE4 (phosphodiesterase 4) inhibitor (IC₅₀ = 74 nM). It reduces TNF-α production in human synovial cells and significantly suppresses experimental arthritis.,
Canonical smiles:CCOC1=C(C=CC(=C1)C(CS(=O)(=O)C)N2C(=O)C3=C(C2=O)C(=CC=C3)NC(=O)C)OC,
Isomeric smiles:CCOC1=C(C=CC(=C1)[C@@H](CS(=O)(=O)C)N2C(=O)C3=C(C2=O)C(=CC=C3)NC(=O)C)OC,
InChi:InChI=1S/C22H24N2O7S/c1-5-31-19-11-14(9-10-18(19)30-3)17(12-32(4,28)29)24-21(26)15-7-6-8-16(23-13(2)25)20(15)22(24)27/h6-11,17H,5,12H2,1-4H3,(H,23,25)/t17-/m1/s1,
InChiKey:IMOZEMNVLZVGJZ-QGZVFWFLSA-N,
IUPAC Name:N-[2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-1,3-dioxoisoindol-4-yl]acetamide
Product details:
This product is manufactured by BioVision, an Abcam company and was previously called 2352 Apremilast. 2352-25 is the same size as the 25 mg size of ab285379.
Protect from air and moisture.
Properties and Storage Information:
Shipped at conditions-Blue Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-It is important to note that this is air sensitive and impurities can occur as a result of air oxidation
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Collaboration
Tony Tang
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