Abcam, ab285439, TLR2-IN-C29

Size: 5mg / 25mg
MW 285.29 Da, Purity >98%. Inhibitor of TLR2/1 and TLR2/6 signaling. It is induced by synthetic and bacterial TLR2 agonists in human HEK-TLR2 and THP-1 cells, but only TLR2/1 signaling in murine macrophages. It prevents the early activation of TLR2-mediated signaling, including NF-κB and MAPKs, as well as MyD88 recruitment to TLR2 in THP-1 cells.
Key facts
CAS number:363600-92-4,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:285.29 Da,
Molecular formula:C16H15NO4,
PubChem:3579893,
Nature:Synthetic,
Solubility:Soluble in DMSO,
Biochemical name:Tlr2-IN-C29,
Biological description:Inhibitor of TLR2/1 and TLR2/6 signaling. It is induced by synthetic and bacterial TLR2 agonists in human HEK-TLR2 and THP-1 cells, but only TLR2/1 signaling in murine macrophages. It prevents the early activation of TLR2-mediated signaling, including NF-κB and MAPKs, as well as MyD88 recruitment to TLR2 in THP-1 cells.,
Canonical smiles:CC1=C(C=CC=C1N=CC2=C(C(=CC=C2)OC)O)C(=O)O,
InChi:InChI=1S/C16H15NO4/c1-10-12(16(19)20)6-4-7-13(10)17-9-11-5-3-8-14(21-2)15(11)18/h3-9,18H,1-2H3,(H,19,20),
InChiKey:WTGMGRFVBFDHGQ-UHFFFAOYSA-N,
IUPAC Name:3-[(2-hydroxy-3-methoxyphenyl)methylideneamino]-2-methylbenzoic acid

Product details:
This product is manufactured by BioVision, an Abcam company and was previously called B2121 TLR2-IN-C29. B2121-5 is the same size as the 5 mg size of ab285439.

Properties and Storage Information:
Shipped at conditions-Blue Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes