Abcam, ab287106, E7820

Size: 5mg / 25mg
MW 336.4 Da, Purity >98%. A small molecule sulfonamide derivative with potential antiangiogenic and antitumor activities. E7820 inhibits angiogenesis by suppressing integrin alpha 2, a cell adhesion molecule expressed on endothelial cells. Inhibition of integrin alpha 2 leads to an inhibition of cell-cell interactions, endothelial cell-matrix interactions, vascular endothelial cell proliferation and angiogenesis.
Key facts
CAS number:289483-69-8,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:336.4 Da,
Molecular formula:C17H12N4O2S,
PubChem:196970,
Nature:Synthetic,
Solubility:>30 mg/ml in DMSO,
Biochemical name:N-(3-cyano-4-methyl-1H-indol-7-yl)-3-cyanobenzene-sulfonamide,
Biological description:A small molecule sulfonamide derivative with potential antiangiogenic and antitumor activities. E7820 inhibits angiogenesis by suppressing integrin alpha 2, a cell adhesion molecule expressed on endothelial cells. Inhibition of integrin alpha 2 leads to an inhibition of cell-cell interactions, endothelial cell-matrix interactions, vascular endothelial cell proliferation and angiogenesis.,
Canonical smiles:CC1=C2C(=CNC2=C(C=C1)NS(=O)(=O)C3=CC=CC(=C3)C#N)C#N,
InChi:InChI=1S/C17H12N4O2S/c1-11-5-6-15(17-16(11)13(9-19)10-20-17)21-24(22,23)14-4-2-3-12(7-14)8-18/h2-7,10,20-21H,1H3,
InChiKey:LWGUASZLXHYWIV-UHFFFAOYSA-N,
IUPAC Name:3-cyano-N-(3-cyano-4-methyl-1H-indol-7-yl)benzenesulfonamide

Product details:
This product is manufactured by BioVision, an Abcam company and was previously called B2600 E7820. B2600-25 is the same size as the 25 mg size of ab287106.

Properties and Storage Information:
Shipped at conditions-Blue Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-It is important to note that this product is reported to be light sensitive, Store in the dark