Abcam, ab307601, Anti-xCT antibody [EPR27115-64]

Size: 20µL / 100µL / 1mL
Anti-xCT antibody [EPR27115-64] (ab307601) is a rabbit monoclonal antibody detecting xCT in Western Blot, Flow Cytometry (Intra), Flow Cytometry, IP, IHC-P, ICC/IF . Suitable for Human, Mouse, Rat . - Biophysical QC for unrivalled batch-batch consistency
Key facts
Host species:Rabbit,
Clonality:Monoclonal,
Clone number:EPR27115-64,
Isotype:IgG,
Carrier free:No,
Reacts with:Rat, Mouse, Human,
Applications:Flow Cyt (Intra), IHC-P, WB, ICC/IF, IPSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:The exact immunogen used to generate this antibody is proprietary information.,
Specificity:We recommend not to boil your lysates before loading to gel when preparing membrane used for western blot. Boiling leads to the formation of aggregates of membrane proteins, leading to unsuccessful migration in gel. Please do not boil your lysate when testing membrane protein.FURTHER INFORMATION ON SPECIFICITY (Chinese Version) available under the product protocols section. This file includes key technical notes of experience when using this product.

Product details:
Anti-xCT antibody [EPR27115-64] (ab307601) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in Flow Cyt (Intra), ICC/IF, IHC-P, IP and WB.
Abcam's high quality manufacturing and validation processes ensure Anti-xCT antibody [EPR27115-64] (ab307601) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility.
Anti-xCT antibody [EPR27115-64] (ab307601) specifically detects xCT (UniProt ID: Q9UPY5; Molecular weight: 56kDa) and is sold in a convenient trial size to enable initial testing (20 µL) and larger sizes for subsequent scaling up experiments (100 µL and 1 mL).
Conjugation-ready, carrier free format available for antibody clone EPR27115-64 -
ab307602
A highly validated xCT (SLC7A11) antibody, essential for studying the cystine/glutamate antiporter SLC7A11, ferroptosis and redox balance. This antibody is crucial in cancer research, particularly in understanding xCT's role in tumor progression and antioxidant defense and is widely used in studies of reactive oxygen species (ROS) and xCT inhibitors for therapeutic applications. SLC7A11 is frequently overexpressed in human cancers. SLC7A11 promotes cystine uptake and glutathione biosynthesis, resulting in protection from oxidative stress and ferroptotic cell death. Recent studies have unexpectedly revealed that SLC7A11 also plays critical roles in glutamine metabolism and regulates the glucose and glutamine dependency of cancer cells. Expression of SLC7A11/xCT correlates with advanced lung cancer stage and predicted a worse 5-year survival.
Patented technology
Our RabMAb
technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to
RabMAb® patents
What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:
- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production
For more information, read more on
recombinant antibodies

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Protein A, Storage buffer-pH: 7.2 - 7.4Preservative: 0.01% Sodium azideConstituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle