Abcam, ab308359, Anti-Swine Influenza A virus G4 EA H1N1 HA Hemagglutinin antibody [HL1342]

Size: 100µL
Rabbit Recombinant Monoclonal Swine Influenza A virus G4 EA H1N1 HA (Hemagglutinin) (A/swine/Henan/SN10/2018) antibody. Carrier free. Suitable for IHC-P, ICC/IF, WB and reacts with Transfected cell line - Swine Influenza A virus samples.
Key facts
Host species:Rabbit,
Clonality:Monoclonal,
Clone number:HL1342,
Isotype:IgG,
Carrier free:Yes,
Reacts with:Swine Influenza A virus,
Applications:WB, IHC-P, ICC/IFSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.

Product details:
What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:
- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production
For more information, read more on
recombinant antibodies
Conjugation ready
Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.
Use our
conjugation kits
for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Protein A, Storage buffer-pH: 7.4Constituents: PBS, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
Swine Influenza A Hemagglutinin often called HA is a surface glycoprotein on the influenza virus particularly H1N1 subtype. HA plays a central role in the initial attachment of the virus to the host cell by binding to sialic acid receptors. This binding facilitates the entry of the virus into the cell. Hemagglutinin weighs approximately 75 kDa. It is expressed on the envelope of the influenza virus and serves as an important antigenic target for immune response.
Biological function summary
Swine Influenza A Hemagglutinin functions to mediate the fusion between the viral envelope and the host cell membrane enabling the release of viral RNA into the host cell. HA operates as part of the viral protein complex within the influenza virus and is essential for viral infectivity. Its ability to mutate and change antigenic properties makes it a constant subject of study in immunology and vaccine development.
Pathways
Hemagglutinin directly interacts with the process of viral endocytosis and membrane fusion. It is a component of the viral life cycle pathway which includes the replication and assembly of viral particles. It works in concert with other viral proteins like neuraminidase which helps in the release of newly formed viral particles from the host cell. These pathways are critical for understanding how the influenza virus replicates and spreads in the host organism.
HA is primarily associated with Influenza illness outbreaks such as the H1N1 flu. This protein's ability to undergo frequent antigenic shifts and drifts complicates the development of effective vaccines making it a significant focus in flu research. Hemagglutinin's relationship with other proteins like neuraminidase contributes to the pathogenicity of flu viruses. Additionally it plays a role in cross-species transmission with strains such as G4 EA H1N1 raising concerns about potential pandemic sources.